SYSTEM AND METHOD FOR INTEGRATING GENOTYPIC INFORMATION AND PHENOTYPIC MEASUREMENTS FOR PRECISION HEALTH ASSESSMENTS

摘要

The present disclosure is directed to a system and method to integrate genotypic information and phenotypic measurements for predicting health related risks. While the genetic information is extracted through efficient training with genotypic data and biological priors, the phenotypic measurements are further integrated into the risk assessing model through updating. The flexibility of this approach enables not just personalized risk assessment in near future, but also a framework to evaluate the value of specific medical tests, clinical decision support, and life actuarial calculations.