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METHOD OF STIMULATING ASYMMETRIC DIVISION OF SATELLITE STEM CELLS
METHOD OF STIMULATING ASYMMETRIC DIVISION OF SATELLITE STEM CELLS
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机译:刺激卫星干细胞不对称分裂的方法
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摘要
The present disclosure provides a method for stimulating asymmetric division of at least some satellite stem cells in a patient suffering from a disease or disorder characterized by satellite cells having an inability, or a reduced ability, to assemble a functional dystrophin-associated glycoprotein complex (DGC) that results in an inability, or reduced ability, to establish cell polarity. The method includes administering to the patient a sufficient amount of an epidermal growth factor receptor (EGFR) pathway activator to stimulate asymmetric division of at least some satellite stem cells.
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