REGENERATIVE MATERIAL OF CONJUNCTIVE TISSUES, SUCH AS BONE, DENTINE OR PULP, UNDERSTANDING CALCIUM SILICATE

摘要

the present invention relates to a regenerative material in the field of regeneration of connective tissues (such as bone, dentin or pulp). more precisely, the present invention relates to a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, comprising: - a porous polymeric matrix with interconnected pores; e - unhydrated calcium silicate particles; wherein: said polymeric matrix is anhydrous; said unhydrated calcium silicate particles have a particle size d50, preferably ranging from 0.05 µm less than the average pore diameter size of the matrix; and said particles of unhydrated calcium silicate being coated on the inner pore walls of the matrix. the present invention also relates to the process for preparing said regenerative connective tissue material. the present invention also relates to the use of said regenerative materials, as, for example, in the dental field; especially, to provide regenerative materials with better biomechanical and osteoinductive properties (ie, good cell migration, adhesion and proliferation; improved mechanical properties; and optimal and controlled biodegradability).