Agents of the International Cancer Research Institute and compounds characterized by the inhibition of C-III (APOC3) apolipoprotein

摘要

This note refers to the agents of iarn, for example, the double chain agents of iarn, who can inhibit the expression of C-III apolproteine gene (also known as APOC3, apoC-III, apoC-III and apoC-III).And the work of agent iarn from APOC3 The IARN Apoc3 agent described in this report can be combined with target ligation, including N- ethyl-galactamin ligation, to facilitate cell management, including liver cells. It also describes the pharmaceutical ingredients containing one or more iarn APOC3 preparations, optionally adding one or more therapeutic products. The staff management site of iarn, APOC3, provides inhibition of APOC3 gene expression,It may also result in a decrease in triglyceride and / or cholesterol levels. The APOC3 agent of the international cancer research institute can be used to treat diseases and diseases related to APOC3, including high triglyceride poisoning, cardiovascular diseases and other related metabolic diseases.