Compositions for pulmonary administration of long-acting muscarinic antagonists and long-acting beta-2 adrenergic receptor agonists and associated methods and systems

摘要

Compositions, methods and systems are provided for pulmonary or nasal delivery of active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.