DEVICE FOR GUIDING CELL MIGRATION AND METHOD OF GUIDING CELL MIGRATION IMPLEMENTING SUCH A DEVICE

摘要

A guide device (1) in which cells (3) are confined between a support surface (2) and a textured surface (6) of a substrate (5), said textured surface (6) having an anisotropic three-dimensional structure (8 ) having a repeat pattern along a repeat axis (X), said repeat pattern having a succession of adjacent guide spaces (15) along the repeat axis (X), each of said guide spaces (15) being adapted to receive at least a part of one of the cells (3) and oriented in a direction of anisotropy (A1) to guide a movement of the cells (3) in the direction of anisotropy (A1).