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HIGH-THROUGHPUT PARALLEL RAMAN SPECTROMETER BASED ON SINGLE CELL DETECTION

机译:基于单细胞检测的高通量平行拉曼光谱仪

摘要

Disclosed is a high-throughput parallel Raman spectrometer for cell detection. Specifically, the Raman spectrometer comprises: a movable platform (9) for placing a sample to be tested, which contains cells; a micro-imaging module for micro-imaging the sample to be tested; a laser focusing module for focusing a laser such that the laser is irradiated to a cell region to be tested, and a Raman signal is excited in a linear array multi-cell manner; a spectrum collection module for collecting a Raman signal generated by a cell irradiated by the laser focused through the laser focusing module; a collection planning and control module for controlling the movable platform to move along a planned route such that the spectrum collection module collects a Raman spectrum of linear-array cells; a Raman spectrum processing module for processing the Raman spectrum from the spectrum collection module to obtain a Raman spectrum signal corresponding to a single cell; and an output module for outputting a detection result.
机译:公开了一种用于细胞检测的高通量平行拉曼光谱仪。具体地说,拉曼光谱仪包括:可移动平台(9),用于放置包含细胞的待测样品;微成像模块,用于对要测试的样品进行微成像;激光聚焦模块,用于聚焦激光,以将激光照射到待测细胞区域,以线性阵列多细胞方式激发拉曼信号;光谱收集模块,用于收集由通过激光聚焦模块聚焦的激光照射的细胞所产生的拉曼信号;收集计划和控制模块,用于控制可移动平台沿计划路线移动,以使光谱收集模块收集线性阵列单元的拉曼光谱。拉曼光谱处理模块,用于处理来自频谱采集模块的拉曼光谱,以获得与单个小区对应的拉曼光谱信号;输出模块,用于输出检测结果。

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