首页> 外国专利> PEGYLATED BORON CLUSTER COMPOUND, ANTITUMOR AGENT INCLUDING PEGYLATED BORON CLUSTER COMPOUND, AND SENSITIZER INCLUDING PEGYLATED BORON CLUSTER

PEGYLATED BORON CLUSTER COMPOUND, ANTITUMOR AGENT INCLUDING PEGYLATED BORON CLUSTER COMPOUND, AND SENSITIZER INCLUDING PEGYLATED BORON CLUSTER

机译:聚乙二醇化硼团簇化合物,包括聚乙二醇化硼团簇化合物的抗氧化剂和含聚乙二醇化硼团簇的敏化剂

摘要

As an enhancer for boron neutron capture therapy, a compound is anticipated which has ideal effects and physical properties in terms of the therapeutic principles of boron neutron capture therapy. As a solution, the present invention provides: a PEGylated boron cluster compound characterized in that a boron cluster having a thiol group binds to a multi-arm polyethylene glycol with a maleimide functional group; an antitumor agent including a PEGylated boron cluster compound; and an enhancer including a PEGylated boron cluster compound used for boron neutron capture therapy.
机译:作为硼中子俘获疗法的增强剂,期望一种化合物,其根据硼中子俘获疗法的治疗原理具有理想的作用和物理性质。作为解决方案,本发明提供了一种聚乙二醇化硼簇化合物,其特征在于,具有硫醇基的硼簇与具有马来酰亚胺官能团的多臂聚乙二醇结合。包含聚乙二醇化硼簇化合物的抗肿瘤剂;增强剂,包括用于硼中子俘获治疗的聚乙二醇化硼簇化合物。

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