METHOD FOR SCREENING ACTIVE MATERIAL USING SKIN EXOGENOUS AGING TARGET, AND ACTIVE MATERIAL FOR IMPROVING SKIN EXOGENOUS AGING

摘要

Disclosed in the present invention are a method for screening an active material, which improves skin exogenous aging, using a skin exogenous aging target, and an active material for improving skin exogenous aging. In the invention, microRNA in the skin is used as a detection basis, the microRNA being any one of or a combination of a plurality of hsa-let-7a-3p, hsa-miR-141-5p, hsa-miR-29a-5p, and hsa-miR-206. The present invention provides a novel regulatory target for the development of cosmetic active ingredients that improve skin exogenous aging.