首页> 外国专利> RECOMBINANT PROTEIN FOR PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE

RECOMBINANT PROTEIN FOR PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE

机译:用于预防或治疗阿兹海默氏病的重组蛋白,以及用于预防或治疗阿兹海默氏病的组合物

摘要

The present invention relates to a recombinant protein for prevention or treatment of Alzheimer's disease, which is recombined on the basis of milk fat globule-EGF factor 8(MFG-E8) protein and has the amino acid sequence of SEQ ID NO: 1. The recombinant protein can delay the onset of Alzheimer's disease or slow down the progression of the disease and further can provide an effect of restoring symptoms associated with degeneration in memory, cognition, and behavior to normal levels. In addition, the present invention relates to a pharmaceutical composition comprising as an active ingredient a recombinant protein for prevention or treatment of Alzheimer's disease, which is recombined on the basis of milk fat globule-EGF factor 8 (MFG-E8) protein and has the amino acid sequence of SEQ ID NO: 1.
机译:本发明涉及一种用于预防或治疗阿尔茨海默氏病的重组蛋白,其基于乳脂球-EGF因子8(MFG-E8)蛋白重组,并具有SEQ ID NO:1的氨基酸序列。重组蛋白可以延迟阿尔茨海默氏病的发作或减慢疾病的进展,并进一步提供将与记忆力,认知和行为退化有关的症状恢复到正常水平的作用。另外,本发明涉及药物组合物,其包含作为预防或治疗阿尔茨海默氏病的重组蛋白作为活性成分,所述重组蛋白基于乳脂球-EGF因子8(MFG-E8)蛋白重组并且具有SEQ ID NO:1的氨基酸序列。

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