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Cellular-based method for determining the potency of defibrotide
Cellular-based method for determining the potency of defibrotide
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机译:基于细胞的去纤蛋白药效测定方法
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#$%^&*AU2020250225A120201105.pdf#####ABSTRACT The present invention relates to cell-based methods for determining the biological activity of defibrotide. In particular, the invention provides a method for assessing the potency of defibrotide by assessing the viability of mammalian cells in the presence of at least one cytotoxic agent and one or more concentrations of defibrotide. Such methods are particularly useful for standardizing pharmaceutical compositions comprising defibrotide.FIGURE1I E C UL0 CIO,) 1/10
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