IN-VITRO METHOD FOR DETECTING AT LEAST ONE NUCLEIC ACID, WHICH IS LOCATED OUTSIDE THE BLOOD CELLS IN WHOLE BLOOD IN THE CASE OF A LIVING BEING, AND DEVICE AND KIT FOR THIS PURPOSE

摘要

The invention relates to an in-vitro method, a device and a kit for detecting at least one nucleic acid (preferably DNA and/or RNA, particularly preferably DNA), which is located outside the blood cells in whole blood in the case of a living being. The advantage of the method according to the invention is that the execution of the method requires less time and equipment that known methods from the prior art, and that the risk of contamination and the risk of loss of cell-free nucleic acid (e.g. cell-free DNA) to be amplified is minimised. The method is therefore more economical and has a higher detection accuracy than known detection methods for cell-free nucleic acids (e.g. cell-free DNA). In addition, in particular, the detection sensitivity is increased relative to detection methods from the prior art, which are based on a dilution of the blood. The invention also relates to a use of the provided device and the provided kit.