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METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS
METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS
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机译:从植物细胞培养物中制备含有鸟苷酸的3- O I>- p I>-香豆酰基酯的组合物的方法,其作为抗疟疾剂用于治疗锥虫病
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摘要
The present invention relates to a method for the production of a (poly)hydroxylated pentacyclic triterpene composition including a 3-O-p-coumaroyl ester of tormentic acid from a plant suspension cell culture, to a pharmaceutical composition comprising at least 3-O-p-coumaroyl ester of tormentic acid for a use in the prevention and/or the treatment of trypanosomiasis, optionally in admixture with other (poly)hydroxylated pentacyclic triterpenes, and to 3-O-p-coumaroyl ester of tormentic acid for its use as an antiparasitic agent for the prevention and/or the treatment of trypanosomiasis, optionally in admixture with other (poly)hydroxylated pentacyclic triterpenes.
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机译:本发明涉及一种从植物悬浮细胞培养物中生产包含聚草酸的3-IOp-香豆酰基酯的(聚)羟基化的五环三萜组合物的方法,所述药物组合物包含:用于预防和/或治疗锥虫病的曲折酸的至少3- Op I>-香豆酰基酯,可选地与其他(多)羟基化的五环三萜混合使用,并与3- 草酸的Op-香豆酰基酯,其用作抗寄生虫剂,用于预防和/或治疗锥虫病,并可选地与其他(聚)羟基化的五环三萜混合使用。
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