首页> 外国专利> PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING

PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING

机译：蛋白酶激活的RECEP-2抑制剂对海洋神经毒性中毒引起的感觉神经病的治疗

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摘要

The present invention relates to the treatment of sensory neuropathy induced by a marine neurotoxic poisoning. The invention further encompasses an in vitro method for producing a neuro-cutaneous model allowing to study the cellular and/or molecular mechanisms involved in said neuropathy, a neuro-cutaneous model obtainable according to said method, and applications thereof.

机译：本发明涉及由海洋神经毒性中毒引起的感觉神经病的治疗。本发明还包括用于产生神经-皮肤模型的体外方法，该方法允许研究涉及所述神经病的细胞和/或分子机制，可根据所述方法获得的神经-皮肤模型和应用。其。 展开▼

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公开/公告号WO2020201572A1

专利类型

公开/公告日2020-10-08

原文格式PDF

申请/专利权人 UNIVERSITÉ DE BRETAGNE OCCIDENTALE;CENTRE HOSPITALIER RÉGIONAL ET UNIVERSITAIRE DE BREST;INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);
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申请/专利号WO2020EP59698

发明设计人 LE GARREC RAPHAELE;LHERONDELLE KILLIAN;MISERY LAURENT;PIERRE OPHELIE;MIGNEN OLIVIER;
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申请日2020-04-05

分类号A61K31/454;A61K39/395;A61K45;A61P25/02;

国家 WO

入库时间 2022-08-21 11:09:08

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3. METHOD FOR PRODUCING MODEL OF EPIDERMAL KERATINOCYTES AFFECTED BY PROTEASE-ACTIVATED RECEPTOR-2 (PAR-2)-INDUCED CHRONIC RENAL FAILURE [P] . 韩国专利： KR20170096687A . 2017-08-25

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