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ATTENUATED AFRICAN SWINE FEVER VIRUS WITH DELETED GENE AND USE OF SAME AS VACCINE

机译:带有减毒基因的减毒非洲猪瘟病毒,并用作疫苗

摘要

Provided is an attenuated African swine fever virus, a gene of which has been deleted, which can be used as a vaccine, a vaccine thereof, and a construction method therefor. The construction method comprises using Chinese epidemic strain Pig/CN/HLJ/2018 of African swine fever, and deleting a virulence gene of the African swine fever virus by means of gene engineering technology, thereby obtaining viruses, which have undergone gene deletion, from which MGF360-505R has been deleted and both CD2V and MGF360-505R have been deleted.
机译:提供了一种已被删除的减毒的非洲猪瘟病毒,其可用作疫苗,其疫苗及其构建方法。该构建方法包括:使用非洲猪瘟的中国流行株Pig / CN / HLJ / 2018,通过基因工程技术缺失非洲猪瘟病毒的毒力基因,从而获得经过基因删除的病毒。 MGF360-505R已被删除,CD2V和MGF360-505R已被删除。

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