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A kit for detecting renal cell damage method for detecting renal tubular cell damage and method for screening a therapeutic agent for renal tubular cell damage
A kit for detecting renal cell damage method for detecting renal tubular cell damage and method for screening a therapeutic agent for renal tubular cell damage
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机译:用于检测肾细胞损伤的试剂盒用于检测肾小管细胞损伤的方法和筛选用于肾小管细胞损伤的治疗剂的方法
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摘要
The present invention relates to a kit for diagnosing cell damage in the glomerulus or renal tubules, and methods for providing information for diagnosing the same and screening a therapeutic substance for the same. As changes in the levels of Sirt1, HIF-1, CA9, and Bnip3 proteins are found in cell damage in the glomerulus or renal tubules, cell damage in the glomerulus or renal tubules caused by hypoxia or drugs can be diagnosed through changes in Sirt1, HIF-1, CA9, and Bnip3 proteins, which may be utilized in the development of cell-based specific diagnostic kits, diagnosis methods, methods for predicting and diagnosing cell damage induced by a drug on the glomerulus or renal tubules, and methods for screening candidate substances.
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