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PEPTIDES AND COMBINATION OF PEPTIDES OF NON-CANONICAL ORIGIN FOR USE IN IMMUNOTHERAPY AGAINST DIFFERENT TYPES OF CANCERS

机译:用于非典型癌症免疫治疗的非典籍多肽和多肽组合

摘要

The present invention relates to peptides, nucleic acids and cells for use in immunotherapy methods. In particular, the present invention relates to immunotherapy for cancer. The present invention is also a tumor-associated T for transfer to a patient by stimulating an anti-tumor immune response or stimulating T cells ex vivo, either alone or in combination with, for example, other tumor-associated peptides capable of serving as an active pharmaceutical component of a vaccine composition. It relates to cell epitopes. The peptide bound to the molecule of the major histocompatibility complex (MHC) or the peptide itself may be a target of antibodies, soluble T cell receptors, and other binding molecules.
机译:本发明涉及用于免疫治疗方法的肽,核酸和细胞。特别地,本发明涉及用于癌症的免疫疗法。本发明还是一种肿瘤相关的T,其通过单独或与例如其他能够作为抗肿瘤药物的肿瘤相关肽结合使用,通过刺激抗肿瘤免疫应答或离体刺激T细胞而转移到患者体内。疫苗组合物的活性药物成分。它涉及细胞表位。与主要组织相容性复合物(MHC)的分子结合的肽或该肽本身可能是抗体,可溶性T细胞受体和其他结合分子的靶标。

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