首页> 外国专利> EF5 Novel Enterococcus faecalis specific bacteriophage EF5 and antibacterial composition comprising the same

EF5 Novel Enterococcus faecalis specific bacteriophage EF5 and antibacterial composition comprising the same

机译:EF5新型粪肠球菌特异性噬菌体EF5和包含其的抗菌组合物

摘要

The present invention is enteric bacteria, in particular Enterococcus ( Enterococcus)faecalis) New bacteriophage having a specific apoptotic function in EF5, a composition for antibiotic containing the bacteriophage, a composition for feed addition, feed, disinfectants or cleaning agents and infectious diseases caused by sheet, comprising administering the bacteriophage on the object aureus It relates to a method of preventing or treating. The method for preventing or treating infectious diseases caused by enterococci using bacteriophage EF5 of the present invention has a very high specificity for enterococci, in particular, Enterococcus faecalis, compared to conventional chemicals such as antibiotics. It has the advantage of being excellent in lytic activity and resistant to physicochemical stimulation by proliferating in enterococci by infecting bacteria. In addition, the bacteriophage EF5 of the present invention is not infected with a host other than bacteria such as humans, animals, plants, and the like, which can solve problems of antibiotic resistant bacteria due to misuse of antibiotics, residues of antibiotics in food, and a wide range of hosts. have. Therefore, the bacteriophage EF5 of the present invention can be used in various fields in the prevention or treatment of infectious diseases caused by enterococci, antibiotic compositions, feed additive compositions, feed, disinfectants, or detergents.
机译:本发明是肠细菌,特别是肠球菌肠球菌) 粪便)在EF5(一种抗生素组合物)中具有特定凋亡功能的新型噬菌体包含噬菌体,用于饲料添加的组合物,饲料,消毒剂或清洁剂以及由片引起的感染性疾病,包括将噬菌体施用于目标金黄色葡萄球菌。涉及一种预防或治疗方法。与常规化学药品例如抗生素相比,使用本发明的噬菌体EF5预防或治疗由肠球菌引起的感染性疾病的方法对肠球菌,特别是粪肠球菌具有非常高的特异性。它具有溶菌活性优异和通过感染细菌在肠球菌中增殖而抗物理化学刺激的优点。另外,本发明的噬菌体EF5没有被除人,动物,植物等细菌外的宿主感染,可以解决由于滥用抗生素,食品中的抗生素残留而引起的对抗生素耐药的细菌的问题。 ,以及各种各样的主机。有。因此,本发明的噬菌体EF5可用于预防或治疗由肠球菌,抗生素组合物,饲料添加剂组合物,饲料,消毒剂或去污剂引起的传染病的各个领域。

著录项

  • 公开/公告号KR102066898B1

    专利类型

  • 公开/公告日2020-01-16

    原文格式PDF

  • 申请/专利权人 주식회사 옵티팜;

    申请/专利号KR20170169631

  • 申请日2017-12-11

  • 分类号C12N7;A01N63;A23K10/16;A23K20/195;A23L3/3571;A61K35/76;C11D3/48;

  • 国家 KR

  • 入库时间 2022-08-21 11:05:30

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