EID3 EID3 MSC- Th17 A Method for Reducing Differentiation or Activity of Th17 Cells Comprising EID3 or EID3 Expressing MSC-Exosome

摘要

The present invention provides a method for differentiating or reducing activity of Th17 cells in vitro comprising EID3 or MSC-exosomes expressing EID3; Medium composition for differentiation or activity reduction of Th17 cells; A pharmaceutical composition for preventing or treating Th17 cell-mediated inflammatory disease; And a food composition for preventing or improving Th17 cell-mediated inflammatory disease. The present invention relates to the treatment and long-term of autoimmune diseases by regulating Th17 cell-mediated immune disease using EID3 protein present in MSC-derived exosomes. It is expected to be used as an effective agent for suppressing transplant rejection.