首页>
外国专利>
Manufacturing method of mutant strain having increased deinoxanthin productivity and the method for deinoxanthin overproduction by controlling cultivation temperature
Manufacturing method of mutant strain having increased deinoxanthin productivity and the method for deinoxanthin overproduction by controlling cultivation temperature
展开▼
机译:脱黄嘌呤生产率提高的突变菌株的制备方法和通过控制培养温度脱黄嘌呤生产过剩的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to a method for producing a mutant strain having high deinoxanthin production capability and a method for mass production of deinoxanthin using temperature control, and to a Deinococcus radiodurans having high deinoxanthin production capability prepared by the method of the present invention. The mutant strain does not have an artificially introduced antibiotic resistance gene even though it has been prepared by introducing a metabolic engineering method. In addition, the DR0862 ( crtB ) and DR1475 ( dxs ) genes are simultaneously inserted through the deinococcus genus mutant strain having a high-producing ability of deinoxanthin, without using an inducer such as IPTG, and by controlling the culture temperature, DR0862 And by controlling the expression of messenger RNA (mRNA) of the DR1475 gene, it is possible to increase the production of deinoxanthin, and thus, it can be usefully used in mass production of deinoxanthin having high antioxidant activity in a very economical way.
展开▼