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RECTAL SUPPOSITORIES BASED ON MODIFIED BACTERIOPHAGE MS2 FOR TARGETED THERAPY OF MALIGNANT SOLID TUMOURS
RECTAL SUPPOSITORIES BASED ON MODIFIED BACTERIOPHAGE MS2 FOR TARGETED THERAPY OF MALIGNANT SOLID TUMOURS
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机译:基于改良细菌噬菌体MS2的直肠栓塞针对恶性固体肿瘤的靶向治疗
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摘要
FIELD: medicine; pharmaceuticals.;SUBSTANCE: invention refers to pharmaceutical industry, biotechnology and can be used to develop a dosage form of an antitumour agent with a wide spectrum of action. Disclosed is a pharmaceutical composition for treating malignant solid tumours, presented in the form of rectal suppositories, which contains a thallium-containing surface modified bacteriophage MS2 as an active component and a hydrophilic base in a weight ratio of 1:1.;EFFECT: invention provides preparing a dosage form of the preparation having high bioavailability and accelerated therapeutic effect.;1 cl, 5 ex
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机译:领域:医学;药物:发明是指制药工业,生物技术,可用于开发具有广泛作用的抗肿瘤剂剂型。本发明公开了一种以直肠栓剂形式存在的用于治疗恶性实体瘤的药物组合物,该药物组合物含有作为活性成分的含surface表面改性噬菌体MS2和重量比为1:1的亲水性碱。提供了制备具有高生物利用度和加速治疗效果的制剂的剂型。; 1 cl,5 ex
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