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DIAGNOSTIC TECHNIQUE FOR THE COMBINED INFECTION IN CHILDREN WITH ACUTE RESPIRATORY INFECTIONS

机译:儿童急性呼吸道感染合并感染的诊断技术

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine and is intended for diagnosing the activity of the combined infection in children with acute respiratory infections. In children with idiopathic leukopenia and febrile convulsions in blood, presence, activity and serotype of herpes virus of type 6, its quantitative characteristics are detected, immunoglobulins IgM, IgG of class are detected, avidity of immunoglobulins IgG of class is determined. If HHV-6 DNA is present in an amount of not less than 104 copies/ml, genotype A, IgM, IgG antibodies with avidity index less than 40 % diagnose active infectious herpes-virus process.;EFFECT: invention provides higher accuracy of diagnosing ensured by complex sequential virological diagnosis with assessment of activity of HHV-6, its genotype and its involvement in development and severity of disease.;1 cl, 2 ex
机译:发明领域本发明涉及药物,旨在诊断患有急性呼吸道感染的儿童中合并感染的活性。在患有特发性白细胞减少症和血液中高热惊厥的儿童中,检测6型疱疹病毒的存在,活性和血清型,检测其定量特征,检测免疫球蛋白IgM,IgG类,确定免疫球蛋白IgG的亲和力。如果HHV-6 DNA的存在量不小于10 4 个/ ml,则亲和力指数小于40%的基因型A,IgM,IgG抗体可诊断为活跃的传染性疱疹病毒过程。效果:通过对HHV-6的活性,其基因型及其参与疾病发展和严重程度的评估,通过复杂的顺序病毒学诊断确保了本发明提供了更高的诊断准确性。[1cl,2 ex

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