首页> 外国专利> METHOD FOR EVALUATING THE CONDITION OF PERIPHERAL BLOOD MONONUCLEAR CELLS IN PULMONARY TUBERCULOSIS PATIENTS

METHOD FOR EVALUATING THE CONDITION OF PERIPHERAL BLOOD MONONUCLEAR CELLS IN PULMONARY TUBERCULOSIS PATIENTS

机译:肺结核患者外周血单核细胞状况的评估方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to a method for evaluating the state of peripheral blood mononuclear cells, involving determining a phospholipid spectrum of membranes of peripheral blood mononuclear cells. Method is characterized by that evaluation is carried out by determining the relative content of fractions of total lysophospholipids, sphingomyelin and phosphatidylcholine phospholipid spectrum membranes of peripheral blood mononuclear cells and calculating a coefficient determined by formula CC=PC2/SM*LPL, where PC is the relative content of phosphatidylcholine, SM - relative content of sphingomyelin, LPL – relative content of total lysophospholipids; if values of this coefficient are less than or equal to 6.7, reduced functional activity of mononuclear cells is diagnosed.;EFFECT: disclosed is a method of evaluating the condition of peripheral blood mononuclear cells.;1 cl, 3 ex
机译:评估外周血单核细胞状态的方法,涉及确定外周血单核细胞膜的磷脂光谱。该方法的特征在于,通过测定外周血单核细胞的总溶血磷脂,鞘磷脂和磷脂酰胆碱磷脂光谱膜的级分的相对含量并计算由式CC = PC 2 /确定的系数来进行评估。 SM * LPL,其中PC是磷脂酰胆碱的相对含量,SM-鞘磷脂的相对含量,LPL-总溶血磷脂的相对含量;如果该系数的值小于或等于6.7,则诊断为单核细胞功能活性降低。;效果:公开了一种评估外周血单核细胞状况的方法。; 1 cl,3 ex

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