TISSUE-ENGINEERING STRUCTURE FOR FILLING BONE TISSUE OF MAXILLOFACIAL AREA

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology, namely to a tissue engineering structure for filling the bone tissue of the maxillofacial region. Construct comprises donor multipotent mesenchymal stromal cells on a carrier, which is represented by 150–200 mcm octacalcium phosphate granules with pore size of 1–5 mcm, on the surface of which there are incubated multipotent mesenchymal stromal cells obtained from the patient's gingival biopsy material and cultivated on a medium of aqueous sol of nanocrystalline cerium dioxide stabilized with citrate ions in concentration of (10–4) - (10–9) M, wherein concentration of multipotent mesenchymal stromal cells is 2 × 10⁷ cells per 1 g of carrier.;EFFECT: invention widens the range of equipment.;1 cl