Nucleoside cyclic phosphate ester compounds that are anti hepatitis C prodrugs based on liver delivery and use thereof

摘要

Liver specific delivery technology (liver delivery)Nucleoside cyclic phosphorus, an antiviral prodrug based on ivery (LSD)Acid ester compound and its use. Specifically, the present invention is represented by formula IMaterials, their isomers, pharmaceutically available salts, hydrates, solvates, and corresponding pharmaceutical compositionsProvide The present invention is directed to the treatment of antiviral viruses, particularly hepatitis C virusesFurther use of the inventive compound or further combination with other antiviral agents.