首页> 外国专利> Composition for promoting proliferation or mucin secretion of goblet cells containing thymosin beta 4 or a derivative thereof as an active ingredient

Composition for promoting proliferation or mucin secretion of goblet cells containing thymosin beta 4 or a derivative thereof as an active ingredient

机译:含有胸腺素β4或其衍生物作为有效成分的促进杯状细胞增殖或粘蛋白分泌的组合物

摘要

The present invention relates to a composition for promoting blast cell proliferation or mucin secretion, comprising thymosin beta 4, an isoform of thymosin beta 4, an analog thereof, or a derivative of thymosin beta 4 as an active ingredient. will be. The composition for promoting mucin secretion comprising thymosin beta 4, its isoform, or a derivative thereof as an active ingredient of the present invention promotes proliferation of goblet cells and increases the secretion amount of mucin. In particular, the mucin secretion promoting composition increases the expression of Muc5AC, Muc1, Muc4 and Muc16. Therefore, it is determined that the composition for promoting the proliferation of mutant cells or secretion of mucin according to the present invention is excellent in the effect of the disease or mucin-related diseases.
机译:本发明涉及用于促进胚细胞增殖或粘蛋白分泌的组合物,其包含胸腺素β4,胸腺素β4的同工型,其类似物或胸腺素β4的衍生物作为活性成分。将。包含胸腺素β4,其同工型或其衍生物作为本发明的活性成分的用于促进粘蛋白分泌的组合物促进杯状细胞的增殖并增加粘蛋白的分泌量。特别地,促进粘蛋白分泌的组合物增加了Muc5AC,Muc1,Muc4和Muc16的表达。因此,可以确定,根据本发明的用于促进突变细胞的增殖或粘蛋白分泌的组合物在疾病或粘蛋白相关疾病的效果方面是优异的。

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