CONCEPTION DE MÉDICAMENT POUR CHARGE UTILE DÉPENDANTE DE L'APPLICATION, DISTRIBUTION PHARMACOCINÉTIQUE CONTRÔLÉE ET CLAIRANCE RÉNALE

摘要

Design and use of an administered drug in the form of a nanoparticle or molecule is described. In certain examples, the nanoparticle has a core and a shell surrounding the core. The core may be configured or designed to provide useful X-ray attenuating properties, gamma ray emission properties, magnetic properties, or therapeutic effects. In certain aspects, the nanoparticle or molecule is sized so as to either distribute from or remain in the blood pool, while still being eliminated by the kidneys.