PROCÉDÉ POUR LA PRODUCTION D'UNE MEMBRANE EN BIOPOLYMÈRES RÉTICULÉE EN DEUX ÉTAPES ET MEMBRANE EN BIOPOLYMÈRES FABRIQUÉE DANS CE PROCÉDÉ

摘要

The fabrication of a double/two-step crosslinked biopolymer membrane for eye trauma repair lies in preparation of a mixed solution of biopolymers consisting of collagen and chitosan, dropwise adding a solution of the primary crosslinking agent from the group of tannins and pouring the solution onto a flat pad and then drying to form a thin primary cross-linked chitosan-collagen membrane with a thickness after drying of 5 to 10 μm. This is then crosslinked in the second stage with a solution of genipin as a secondary crosslinking agent.