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Immune consolidation after stem cell transplant for CD20+ nonhodgkin’s lymphoma using multiple infusions of autologous activated t cells (ATC) with anti-cd3 x anti-cd20 bispecific antibody (CD20Bi) to improve graft-vs-lymphoma effects

机译：干细胞移植治疗CD20 +非霍奇金淋巴瘤后的免疫巩固，方法是多次注入自体激活T细胞（ATC）和抗cd3 x抗cd20双特异性抗体（CD20Bi）以改善移植物抗淋巴瘤的作用

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Lum L.G.; Davol P.; Colvin G.; Rathore R.; Abedi M.; Palushock E.; Olson A.; Tarro T.; Quesenberry P.;
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1. Activated T cells from umbilical cord blood armed with anti-CD3 x anti-CD20 bispecific antibody mediate specific cytotoxicity against CD20+ targets with minimal allogeneic reactivity: a strategy for providing antitumor effects after cord blood transplants. [J] . Thakur A, Sorenson C, Norkina O, Transfusion: The Journal of the American Association of Blood Banks . 2012,第1期

机译：带有抗CD3 x抗CD20双特异性抗体的脐带血中活化的T细胞以最小的同种异体反应性介导针对CD20 +靶标的特异性细胞毒性：一种在脐血移植后提供抗肿瘤作用的策略。
2. Immunotherapy with FBTA05 (Bi20), a trifunctional bispecific anti-CD3 x anti-CD20 antibody and donor lymphocyte infusion (DLI) in relapsed or refractory B-cell lymphoma after allogeneic stem cell transplantation: study protocol of an investigator-driven, open-label, non-randomized, uncontrolled, dose-escalating Phase I/II-trial [J] . Raymund Buhmann, Stanglmaier Michael, Hess Juergen, Journal of Translational Medicine . 2013,第1期

机译：同种异体干细胞移植后复发或难治性B细胞淋巴瘤中使用三功能双特异性抗CD3 x抗CD20抗体FBTA05（Bi20）和供体淋巴细胞输注（DLI）进行免疫治疗：研究者驱动的开放标签研究方案，非随机，不受控制，剂量递增的I / II试验阶段
3. Emerging Clinical Activity of REGN1979, an Anti-CD20 x Anti-CD3 Bispecific Antibody, in Patients with Relapsed/Refractory Follicular Lymphoma (FL), Diffuse Large B-Cell Lymphoma (DLBCL), and Other B-Cell Non-Hodgkin Lymphoma (B-NHL) Subtypes [J] . Bannerji Rajat, Arnason Jon E., Advani Ranjana, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：RegN1979的临床活性，抗CD20 x抗CD3双特异性抗体，复发/难治滤泡淋巴瘤（FL），弥漫性大B细胞淋巴瘤（DLBCL）和其他B细胞非霍奇金淋巴瘤（B. -NHL）亚型
4. Improved T Cell Activation Bioassays to Advance the Development of Bispecific Antibodies and Engineered T Cell Immunotherapies [C] . Gopal Krishnan, Pete Stecha, Denise Garvin, Protein Engineering Summit. . 2018

机译：改进的T细胞活化生物测定促进双特异性抗体和工程化T细胞免疫检查的发育
5. Correlates of fatigue in lymphoma patients undergoing autologous peripheral blood stem cell transplantation. [D] . El-Banna, Majeda Mohammed. 2004

机译：与进行自体外周血干细胞移植的淋巴瘤患者疲劳相关。
6. Activated T cells from umbilical cord blood armed with anti-CD3 × anti-CD20 bispecific antibody mediate specific cytotoxicity against CD20+ targets with minimal allogeneic reactivity: a strategy for providing antitumor effects after cord blood transplants [O] . Archana Thakur, Carly Sorenson, Oxana Norkina, -1

机译：从脐带血活化的T细胞与抗CD3武装×抗CD20双特异性抗体中介特异性针对以最小的异体反应CD20 +细胞毒性的目标：提供脐带血移植后的抗肿瘤效果的策略
7. Targeting Myeloma Stem Cells with T Cells Armed with Anti-CD3 X Anti-CD20 Bispecific Antibody (CD20BI) Prior to ASCT Leads to Development of Anti-Myeloma Immune Responses Post Autologous Stem Cell Transplant That Can Be Boosted with Targeted T Cells [O] . Lawrence L.G., Archana T., Muneer A., 2012

机译：在ASCT之前，将具有抗CD3 X抗CD20双特异性抗体（CD20BI）的T细胞靶向骨髓瘤干细胞导致自体干细胞移植后抗骨髓瘤免疫反应的发展，可以用靶向T细胞增强

Immune consolidation after stem cell transplant for CD20+ nonhodgkin’s lymphoma using multiple infusions of autologous activated t cells (ATC) with anti-cd3 x anti-cd20 bispecific antibody (CD20Bi) to improve graft-vs-lymphoma effects

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