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Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

机译：胰高血糖素基因（GCG）rs4664447的G等位基因纯合子携带者的特征是禁食和胰岛素，胰高血糖素和胰高血糖素样肽（GLP）-1的水平降低

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The glucagon gene (GCG) encodes several hormones important for energy metabolism: glucagon, oxyntomodulin and glucagon-like peptide (GLP)-1 and -2. Variants in GCG may associate with type 2 diabetes, obesity and/or related metabolic traits.

机译：胰高血糖素基因（GCG）编码对能量代谢重要的几种激素：胰高血糖素，胃泌素调节素和胰高血糖素样肽（GLP）-1和-2。 GCG的变异可能与2型糖尿病，肥胖症和/或相关的代谢特征有关。

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Torekov S S; Ma L; Grarup Niels; Hartmann B; Hainerová I A; Kielgast U; Kissow Hannelouise; Rosenkilde Mona; Lebl J; Witte D R; Jørgensen T; Sandbaek A; Lauritzen T; Madsen O D; Wang J; Linneberg Allan René; Madsbad Sten; Holst J J; Hansen T; Pedersen O; GIANT Consortium;
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1. Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1 [J] . S. S. Torekov, L. Ma, N. Grarup, Diabetologia . 2011,第11期

机译：胰高血糖素基因（GCG）rs4664447的G等位基因纯合子携带者的特征是禁食和胰岛素，胰高血糖素和胰高血糖素样肽（GLP）-1的水平降低
2. Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits [J] . A. P. Gjesing, C. T. Ekstrøm, H. Eiberg, Diabetologia . 2012,第5期

机译：空腹和口服葡萄糖刺激水平的葡萄糖依赖性促胰岛素多肽（GIP）和胰高血糖素样肽1（GLP-1）是高度家族性状
3. Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study [J] . M. Laakso, J. Zilinskaite, T. Hansen, Diabetologia . 2008,第3期

机译：在EUGENE2研究中，空腹血糖受损和/或葡萄糖耐量受损的人群的胰岛素敏感性，胰岛素释放和胰高血糖素样肽-1水平
4. Quantitation of Glucagon-like peptide-1, GLP-1 (7-36) amide, and the DPP4-catalyzed degradation product GLP-1 (9-36) amide by LC/MS [C] . Rong-Sheng Yang, Yan-Hui Liu, Aileen Soriano, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：通过LC / MS定量胰高血糖素肽-1，GLP-1（7-36）酰胺和DPP4催化的降解产物GLP-1（9-36）酰胺
5. Backbone modification of glucagon-like peptide-1 (GLP-1) to alter signaling at the GLP-1 receptor. [D] . Hager, Marlies Veronica. 2017

机译：胰高血糖素样肽1（GLP-1）的骨干修饰，以改变GLP-1受体处的信号传导。
6. Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. [O] . D J Drucker, J Philippe, S Mojsov, 1987

机译：胰高血糖素样肽I刺激大鼠胰岛细胞系中的胰岛素基因表达并增加环AMP含量。
7. Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study [O] . M. Laakso, J. Zilinskaite, T. Hansen, 2007

机译：胰岛素敏感性，胰岛素释放和胰高血糖素样肽-1水平在禁食葡萄糖受损和/或葡萄糖耐受性的葡萄糖耐受性中的研究

Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

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