Enantioselective Total Synthesis of (+)-Salvileucalin B

摘要

An enantioselective total synthesis of the diterpenoid natural product (+)-salvileucalin B is reported. Key findings include aud copper-catalyzed arene cyclopropanation reaction to provide the unusualud norcaradiene core and a reversible retro-Claisen rearrangement of aud highly functionalized norcaradiene intermediate.