首页> 外文OA文献 >Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N-Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression.

【2h】

Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N-Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression.

机译：Ly3020371，效率和选择性代谢谷氨酸（Mglu）2/3受体拮抗剂和氯胺酮，在啮齿动物的非竞争性N-甲基-D-天冬氨酸受体拮抗剂中的比较效果：证据支持使用MGLU2 / 3拮抗剂，用于治疗抑郁症。

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
相似文献
相关主题

著录项

作者
J.M. Witkin; S.N. Mitchell; K.A. Wafford; G. Carter; G. Gilmour; J. Li; B.J. Eastwood; C. Overshiner; X. Li; L. Rorick-Kehn; K. Rasmussen; W.H. Anderson; A. Nikolayev; V.V. Tolstikov; M.-S. Kuo; J.T. Catlow; R. Li; S.C. Smith; C.H. Mitch; P.L. Ornstein; S. Swanson; J.A. Monn;
展开▼
作者单位

展开▼
年度 2017
总页数
原文格式 PDF
正文语种
中图分类

相似文献

外文文献
中文文献
专利

1. Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]. [J] . Satow A, Maehara S, Ise S, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2008,第2期

机译：代谢型谷氨酸受体1拮抗剂与代谢型谷氨酸受体5拮抗剂和代谢型谷氨酸受体2/3激动剂在啮齿类动物中的药理作用：选择性变构代谢型谷氨酸受体1拮抗剂FTIDC的详细研究[4- [1-（ [2-氟吡啶-3-基）-5-甲基-1H-1,2,3-三唑-4-基] -N-异丙基-N-甲基-3,6-二氢吡啶-1（2H）-羧酰胺]。
2. Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 r [J] . Bruno V, Battaglia G, Kingston A, Neuropharmacology . 1999,第2期

机译：有效和选择性的mGlu1a代谢型谷氨酸受体拮抗剂（+）-2-甲基-4羧苯基甘氨酸（LY367385）的神经保护活性：与LY357366的比较，LY357366是对mGlu1a和mGlu5 r具有相同亲和力的广谱拮抗剂
3. Serotonin-1A receptor stimulation mediates effects of a metabotropic glutamate 2/3 receptor antagonist, 2S-2-amino-2-(1S,2S-2-carboxycycloprop-1-yl)- 3-(xanth-9-yl)propanoic acid (LY341495), and an N-methyl-D-aspartate receptor antagonist, ketamine, in the novelty-suppressed feeding test [J] . FukumotoK., IijimaM., ChakiS. Psychopharmacology . 2014,第11期

机译：5-羟色胺-1A受体刺激介导代谢型谷氨酸2/3受体拮抗剂2S-2-氨基-2-（1S，2S-2-羧基环丙-1-基）-3-（黄酮-9-基）丙酸的作用（LY341495）和一种N-甲基-D-天冬氨酸受体拮抗剂氯胺酮在新颖性抑制喂养试验中
4. Mitochondrial Superoxide Production and MnSOD Activity after Exposure to Agonist and Antagonists of Ionotropic Glutamate Receptors in Hippocampus [C] . LIDIJA RADENOVI?, VESNA SELAKOVI?, GORDANA KARTELIJA International Biophysics Symposium . 2005

机译：暴露于海马的激动剂和拮抗剂后的线粒体超氧化物生产和MNSOD活性，在海马中的离子胶质谷氨酸受体
5. Mechanism of block and behavioral effects of the N-methyl-D-aspartate receptor antagonists memantine and ketamine. [D] . Kotermanski, Shawn Edward. 2008

机译：N-甲基-D-天冬氨酸受体拮抗剂美金刚和氯胺酮的阻滞和行为作用机理。
6. Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats [O] . Matthias E. Liechti, Athina Markou -1

机译：mGlu5受体拮抗剂MPEP和mGlu2 / 3受体拮抗剂LY341495对尼古丁自我给药和与尼古丁戒断相关的奖赏缺陷的相互作用
7. Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats [O] . Matthias E. Liechti, Athina Markou 2007

机译：MGLU5受体拮抗剂MPEP和MGLU2 / 3受体拮抗剂LY341495对大鼠尼古丁戒断的尼古丁自我给药和奖励缺陷的互动效果
8. Mercuric Ions are Potent Noncompetitive Antagonists of Human Brain Kainate Receptors Expressed in 'Xenopus oocytes'. [R] . Umbach, J. A., Gundersen, C. B. 1989

机译：汞离子是非洲爪蟾卵母细胞中表达的人脑红藻氨酸受体的强效非竞争性拮抗剂。

Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N-Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression.

著录项

相似文献

相关主题

期刊订阅