Behavioral Risk Reduction Strategies for Chronic Indicators and High-Risk Factors for Premenopausal AAW with a Prevealence for CHD.

摘要

One of every five women in the United States has some form of cardiovascular disease (CVD). In 1996, approximately 500,037 women died from CVD. Premenopausal African American women (AAW) have a rate of death from coronary heart disease (CHD) almost four times greater than their white counterparts. Therefore, the specific aims of this one-year study were threefold: (1) begin to specify the risk factors for CHD in premenopausal AAW (1845 years old); (2) determine if there are particular genetic phenotypes or genotypes, including lipoprotein, apolipoprotein E, endothelin-1, tumor necrosis factor alpha, and mutations within the beta subunit of the epithelial sodium channel, which are genetic predictors for CHD, hypertension, and overt diabetes in premenopausal AAW; and (3) pilot test the effect of a culturally appropriate comprehensive behavioral risk reduction program (CACBRRP) designed to reduce risk factors for CHD. Nine research questions were generated and tested.