Childhood Exposures to Pesticides May Contribute to Obesity and Diabetes in Adults.

摘要

Dr. Ted Slotkin at the Duke University SRP studies the neurotoxic and neurodevelopmental impacts of exposure to organophosphate (OP) pesticides. His research team has made significant discoveries – identifying mechanisms of neurotoxicity that do not involve cholinesterase inhibition; determining that organophosphates are damaging to neural cell replication and differentiation at exposure levels below the threshold for significant inhibition of cholinesterase; and demonstrating that the adverse effects of organophosphates on neurodevelopment are shared by other Superfund chemicals that can target similar events, such as divalent heavy metals and organochlorines.