SERUM ENZYME ACTIVITY IN THE RABBIT FOLLOWING WHOLE-BODY IRRADIATION

摘要

Data are presented on alterations in serum enzyme activity following whole-body irradiation of rabbits at a dosage level of 750r. Of the 14 enzymes investigated, no single enzyme was shown to be a better early indicator of radiation trauma than glutamic oxalacetic transaminase.nEvidence is presented that at least 3 of the enzymes are significantly lower in the serum of irradiated animals 6 hours after radiation than they are in the sham controls, suggesting either inactivation or interference with synthesis.nOf the 14 enzymes studied, 4 were significantly elevated, 3 were lowered, and 7 remained unchanged within an interval of 24 hours after exposure.