Assessing the Hazard Potential of Chemical Substances.

摘要

The ability to identify and specify the thermal instability of chemical substances has been appraised as a result of examining certain test methods used to measure explosive sensitivity, and certain computer programs designed to estimate reaction hazards from a thermochemical approach. The bond dissociation energy emerges as the parameter giving the best correlation with material sensitivity. The computer programs over-emphasize explosive power as opposed to explosive sensitivity and label many compounds hazardous when they are not. At present, the authors recommend that regulations specifying the handling and transport of commodities should follow the concept of self-reactivity based upon functional groups (i.e., nitro, nitramine, peroxide, azide, etc.).