Growth Factors and Tension-Induced Skeletal Muscle Growth

摘要

Tests were conducted to determine whether acute muscle wasting in a hindlimb unload mouse model could be reduced by rhGH-secreting muscle organoid implants. Initial studies were performed with the plant plantaris muscle since it is more growth hormone sensitive than the soleus. It was determined that tissue culture equivalent of the hindlimb unloading animal model and it may become the standard tissue culture model for ground-based and flight studies of muscle wasting in microgravity.