Mechanisms of uranium intoxication in bone - An approach to the study of detoxification methods. Final report for the period December 1989 - December 1993

摘要

Studies were performed employing Wistar rats of different ages, submitted to either toxic or lethal doses of uranyl nitrate and to topical applications of aliquots containing uranium. Different detoxifying agents were applied at different times and frequencies. The results indicate that biphosphonates could be considered as an excellent preventive agent in uranyl nitrate intoxications. The most striking finding involves the use of EHBP to prevent mortality. 10 refs, 4 figs, 1 tab. (Atomindex citation 28:027861)