Final report for LDRD project (open quotes)A new approach to protein function and structure prediction(close quotes)

摘要

This report describes the research performed under the laboratory-Directed Research and Development (LDRD) grant (open quotes)A new approach to protein function and structure prediction(close quotes), funded FY94-6. We describe the goals of the research, motivate and list our improvements to the state of the art in multiple sequence alignment and phylogeny (evolutionary tree) construction, but leave technical details to the six publications resulting from this work. At least three algorithms for phylogeny construction or tree consensus have been implemented and used by researchers outside of Sandia.