Survival of Cultured Mammalian Cells Irradiated at Various Depths in the Lampf Negative Pion Therapy Beam

摘要

Cultured human kidney T-1 cells were irradiated in flasks or on coverslips at different depths in a water phantom using the Clinton P. Anderson Meson Physics Facility (LAMPF) negative pion beam. Studies of cell survival and division delay as a function of depth and recovery between doses indicate RBEs of 1.8 +- 0.3 and an ability of cells to recover between two doses of stopping pions.