Histocompatibility Typing in Mongrel Populations:Man and Dog. Final Report for Period March 1, 1968--February 28, 1977.

摘要

Assorted procedures for controlling graft vs. host reaction by pretreatment of marrow with antithymocyte sera,anti-lymphocyte sera,anti-brain (anti-theta) sera,anti-globulin sera,and Fab preparations were tried in dogs and mice. These procedures,whose modus operandi is an intent to remove thymus-conditioned lymphocytes from the donor marrow,have not proved successful to date primarily because of associated damage to hematopoietic stem cell potential. (ERA citation 02:040007)