Nasal Airway Anatomy and Inhalation Deposition in Experimental Animals and People

摘要

The anatomical characteristics of the nasal cavities of various experimental animals and man have been presented along with particle deposition considerations. There are a number of differences and similarities between the species. Perhaps one of the most obvious examples of anatomical differences is in the structure of the turbinate regions. Some of the differences could affect deposition of various sized particles in the nasal cavities. A degree of caution, therefore, has to be exercised in extrapolating the nasal deposition characteristics from one species to another. Simple scaling calculations may not be sufficient. (ERA citation 07:058219)