Expert Systems Technology Applied to Instrument Operation and Data Acquisition of a Triple Quadrupole Mass Spectrometer (TQMS)

摘要

This presentation covers the work done at Lawrence Livermore National Laboratory by some computer programmers and analytical chemists specializing in mass spectrometry to develop an expert system for real-time tuning and optimization of operations of a triple quadrupole mass spectrometer (TQMS). This capability is important to increase the sensitivity possible for selected compounds throughout the entire mass range of the instrument, rather than settling for the traditional normalized calibration which lowers sensitivity at both ends of the mass scale. (ERA citation 11:006130)