Properties of Dendritic Polymers 2: Generation Dependence of the Physical Properties of Poly(amidoamine) Dendrimers

摘要

Dendritic polymers, or dendrimers, represent a new class of macromolecules characterized by an ultra-branched molecular architecture generated by a novel synthetic route developed in the mid-1980s. As the synthetic science of these molecules matures, the search for applications of them is becoming increasingly active. However, a lack of physical property data has made the identification of suitable application and technology areas that are ripe for exploitation of dendrimers difficult. The purpose of this series of reports is to compile, in the most concise form possible, some fundamental physical property information about dendrimers. The focus is on the behavior of poly(amidomine) or PAMAM dendrimers, which were developed in the United States and are produced domestically by Dendritech, Inc., of Midland, Michigan. In this report, the second in our series, the effect of molecular size or 'generation' of the dendritic polymers on their physical properties is highlighted. The first report, ARL-TR-1606 was published in May 1998 and was focused on the general physical behavior of a mid-sized (Generation 5) PAMAM dendrimer. The third report, slated for completion in early 1999, will focus on 'end group' chemistry dependence of PAMAM dendrimers.