Preparation of Burkholderia pseudomallei Polysaccharide-CRM197 Conjugate, a Potential Vaccine Candidate for Glanders and Melioidosis

摘要

Current ststus treatment of melioidosis and glanders: (1) Burkholderia mallei and B. pseudomallei are the causative agents for glanders and melioidosis, respectively; (2) Both of these organisms have been considered as potential agents for biological warfare and biological terrorism; (3) Currently, these infections are treated with antibiotics; (4) Currently, no vaccines are available for protection against glanders and melioidosis.