Novel Approach for the Identification of Pharmacophores Through Differential Toxicity Analysis of Estrogen Receptor Positive and Negative Cell Lines

摘要

This grant was awarded to the PI at Louisiana State University. He left there in Aug 2006 and with the assistance of Grant Manager, Dr. Carole Christian, it was transferred to the University of Louisville where he started Apr 2007. Minimal work was done on the project prior to departure from LSU and minimal funds were expended. This project was essential to my obtaining an appointment as an Associate Professor of Medicine at the University of Louisville's James Graham Brown Cancer Center, along with significant startup package, and my involvement as a Project PI on the Brown Cancer Center's NIH- funded Molecular Targets Program. Currently, my new laboratory has been equipped with the needed computer hardware and software. I anticipate the postdoctoral fellow hired to participate on the project will start by Aug 6, 2007, and given the revised timeline for this project, I expect that it will be completed on time and as planned.