Are We Listening to Music or Noise? Use of the Lyapunov Exponent for Comprehensive Assessment of Heart Rate Complexity During Hemorrhage in Sedated Conscious Miniature Swine.

摘要

Objectives: Application of tools from nonlinear dynamics for calculation of changes in heart rate complexity assumes presence of deterministic chaotic trends in the investigated data. Calculation of the largest Lyapunov exponent (LLE) is a standard method for confirmation of whether such trends are present and is used to characterize the level of chaos in complex physiologic systems. We sought to evaluate the utility of LLE for that purpose during severe pump-controlled exponential hemorrhagic shock.