Automation and Preclinical Evaluation of a Dedicated Emission Mammotomography System for Fully 3-D Molecular Breast Imaging

摘要

The overall objective of this proposal is to automate the acquisition sequences and optimize the performance of a 3-D dedicated SPECT breast imaging system. A retrospective study of 103 clinical MRI uncompressed breast scans was conducted to create surface renderings of the uncompressed breasts and analyze how to adapt existing acquisition orbits for varying breast shapes. Automated laser-guided SPECT contouring hardware and software were implemented. An observer-based study directly comparing 3D dedicated SPECT and 2D planar scintimammography was completed, concluding that statistically significantly.