Histochemical Study of Gastric Mucosubstances after Thermal Injury: Correlation with Endoscopic Evidence of Acute Gastroduodenal Disease.

摘要

A relationship between severe thermal injury and acute gastrointestinal lesions has been documented. Many factors have been implicated in the pathogenesis of these acute lesions. Gastric hypersecretion has not been consistently found in the patients who develop Curling's ulcer. A change in the protective gastric mucous barrier in the presence of normal gastric acid output has been suggested as an important etiologic factor in development of these acute gastroduodenal lesions.