Sebaceous Gland Carcinoma of the Eyelid. Following radiation Therapy for Cavernous Hemangioma of the Face.

摘要

A 37-year-old woman had received multiple radiation treatments between the ages of 6 months and 15 years for an extensive cavernous hemangioma of the left side of the face. At age 27, a biopsy specimen disclosed squamous cell carcinoma arising in chronic radiodermatitis. Multiple cutaneous lesions were excised surgically, and extensive skin grafting was performed. At age 35, she developed a tumor of the left upper and lower eyelids that extended into the orbit, which proved to be a sebaceous gland carcinoma. Following left orbital exenteration, the tumor promptly recurred in the socket. The patient died with widespread metastatic lesions. This case represents the 4th example of postradiation sebaceous gland carcinoma of the eyelids, it differs from previously reported cases in that radiation therapy had been given for a benign cutaneous condition.